منابع مشابه
Intracellular Transport: Kinesins Working Together
While most in vitro experiments with motor proteins focus on the behavior of individual motors, in cells most cargo are transported by multiple motors and even multiple classes of motor. How these motors cooperate and compete in transporting cargo is not clear. Recent experimental and theoretical work suggests that motors attached to a given cargo interact in both expected and unexpected ways.
متن کاملMyosins pull together—separately
D on’t tell your high school football coach, but it is possible to have teamwork even if nobody’s in charge. Inside a cell, for example, myosin VI motors work in concert to haul cargoes along the actin cytoskeleton, Sivaramakrishnan and Spudich reveal (1). Instead of providing muscle power, myosin VI is one of the unconventional myosins whose job is intracellular transportation. Researchers hav...
متن کاملFlagellar Motility: All Pull Together
Eukaryotic flagella produce a swimming force by coordinating thousands of dynein motor proteins. Recent work provides new clues into how this coordination is achieved.
متن کاملCatastrophic Kinesins Piecing Together Their Mechanism by 3D Reconstruction
Kin Is, kinesins with an internal catalytic domain, de-polymerize microtubules from both ends, and the KIF2C crystal structure presented by ([this issue of Cell]) provides provocative evidence to support the theory that the highly conserved sequences are critical structural elements in these catastrophic kinesins.
متن کاملPotassium channels: Putting the parts together
Potassium channels are central to the electrical activity of the nervous system. They are also widespread in many other cell types and among organisms, both prokaryotic and eukaryotic. Voltage-gated potassium channels, generally termed Kv channels, are complex membrane proteins that form a K+ ion-selective pore that opens and closes in response to changes in voltage across a cell membrane. Kv c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2008
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1804rr5